CD47 (NM_001777) Human Recombinant Protein

• Background:

  This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

• Synonyms:

  IAP; MER6; OA3

• Gene ID:

  961

• UniProt:

  Q08722

• Accession Number mRNA:

  NM_001777

• Chromosomal Location:

  3q13.12

• Expression System:

  HEK293

• Tag:

  C-Fc

• Related Pathways:

  ECM-receptor interaction

• Field of Research:

  ECM-receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  35.21

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD47

• Species:

  Human

• Protein ID:

  NP_001768

• Overview:

  Purified recombinant protein of Homo sapiens CD47 molecule (CD47), residues 19-141aa, with C-terminal Fc tag, expressed in HEK293 cells.

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/961

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q08722

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001777

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001768