CD28 (NM_006139) Human Recombinant Protein

• Background:

  The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

• Synonyms:

  Tp44

• Gene ID:

  940

• UniProt:

  P10747

• Accession Number mRNA:

  NM_006139

• Chromosomal Location:

  2q33.2

• Expression System:

  HEK293

• Tag:

  C-Fc

• Related Pathways:

  Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

• Field of Research:

  Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  40 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD28

• Species:

  Human

• Protein ID:

  NP_006130

• Overview:

  Purified recombinant protein of Human CD28 molecule (CD28), with C-terminal Fc tag, expressed in human cells

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/940

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10747

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006139

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006130