PAFAH (PLA2G7) (NM_001168357) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009]

• Synonyms:

  LDL-PLA2; LP-PLA2; PAFAD; PAFAH

• Gene ID:

  7941

• UniProt:

  Q13093

• Accession Number mRNA:

  NM_001168357

• Chromosomal Location:

  6p12.3

• Expression System:

  HEK293

• Tag:

  C-DDK/His

• Related Pathways:

  Ether lipid metabolism, Metabolic pathways

• Field of Research:

  Ether lipid metabolism, Metabolic pathways

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  51 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PLA2G7

• Species:

  Human

• Protein ID:

  NP_001161829

• Overview:

  Purified recombinant protein of human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7 / Lp-PLA2), transcript variant 2, with C-terminal DDK/His tag, expressed in human cells, 20 µg

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7941

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13093

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001168357

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001161829