CCN2 (NM_001901) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]

• Synonyms:

  CTGF; HCS24; IGFBP8; NOV2

• Gene ID:

  1490

• UniProt:

  P29279, Q5M8T4

• Accession Number mRNA:

  NM_001901

• Chromosomal Location:

  6q23.2

• Expression System:

  Sf9

• Tag:

  C-DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  35.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CCN2

• Species:

  Human

• Protein ID:

  NP_001892

• Overview:

  Recombinant protein of human connective tissue growth factor (CTGF), residues 27-349aa, secretory expressed with GP67 signal peptide, with C-terminal DDK tag, expressed in sf9, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1490

• Uniprot URL:

  https://www.uniprot.org/uniprot/P29279

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001901

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001892