Hsp60 (HSPD1) (NM_199440) Human Recombinant Protein

• Background:

  This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

• Synonyms:

  CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13

• Gene ID:

  3329

• UniProt:

  P10809, A0A024R3X4

• Accession Number mRNA:

  NM_199440

• Chromosomal Location:

  2q33.1

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  RNA degradation, Type I diabetes mellitus

• Field of Research:

  RNA degradation, Type I diabetes mellitus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol

• Function:

  Druggable Genome, Stem cell - Pluripotency

• Molecular Weight:

  61.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HSPD1

• Species:

  Human

• Protein ID:

  NP_955472

• Overview:

  Recombinant protein of human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3329

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10809

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_199440

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_955472