STOML2 (NM_013442) Human Recombinant Protein

• Background:

  Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HSPC108; SLP-2

• Gene ID:

  30968

• UniProt:

  Q9UJZ1

• Accession Number mRNA:

  NM_013442

• Chromosomal Location:

  9p13.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

• Function:

  Druggable Genome

• Molecular Weight:

  38.5

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  STOML2

• Species:

  Human

• Protein ID:

  NP_038470

• Overview:

  Recombinant protein of human stomatin (EPB72) -like 2 (STOML2), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/30968

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UJZ1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013442

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_038470