RPL10A (NM_007104) Human Recombinant Protein

• Background:

  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a) . As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

• Synonyms:

  Csa-19; CSA19; L10A; NEDD6

• Gene ID:

  4736

• UniProt:

  P62906

• Accession Number mRNA:

  NM_007104

• Chromosomal Location:

  6p21.31

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Ribosome

• Field of Research:

  Ribosome

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

• Molecular Weight:

  24.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RPL10A

• Species:

  Human

• Protein ID:

  NP_009035

• Overview:

  Recombinant protein of human ribosomal protein L10a (RPL10A), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4736

• Uniprot URL:

  https://www.uniprot.org/uniprot/P62906

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007104

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_009035