SCN2B (NM_004588) Human Recombinant Protein

• Background:

  The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015]

• Synonyms:

  ATFB14

• Gene ID:

  6327

• UniProt:

  O60939, Q5U0K8

• Accession Number mRNA:

  NM_004588

• Chromosomal Location:

  11q23.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Druggable Genome, Ion Channels: Sodium, Transmembrane

• Molecular Weight:

  24.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SCN2B

• Species:

  Human

• Protein ID:

  NP_004579

• Overview:

  Recombinant protein of human sodium channel, voltage-gated, type II, beta (SCN2B), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6327

• Uniprot URL:

  https://www.uniprot.org/uniprot/O60939

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004588

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004579