GCAP3 (GUCA1C) (NM_005459) Human Recombinant Protein

• Background:

  Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca (2+) -sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  GCAP3

• Gene ID:

  9626

• UniProt:

  O95843

• Accession Number mRNA:

  NM_005459

• Chromosomal Location:

  3q13.13

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Olfactory transduction

• Field of Research:

  Olfactory transduction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

• Molecular Weight:

  23.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GUCA1C

• Species:

  Human

• Protein ID:

  NP_005450

• Overview:

  Purified recombinant protein of Human guanylate cyclase activator 1C (GUCA1C), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9626

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95843

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005459

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005450