ENDOGL1 (EXOG) (NM_005107) Human Recombinant Protein

• Background:

  This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]

• Synonyms:

  ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB

• Gene ID:

  9941

• UniProt:

  Q9Y2C4

• Accession Number mRNA:

  NM_005107

• Chromosomal Location:

  3p22.2

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Apoptosis

• Field of Research:

  Apoptosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  36.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EXOG

• Species:

  Human

• Protein ID:

  NP_005098

• Overview:

  Purified recombinant protein of Human endo/exonuclease (5'-3'), endonuclease G-like (EXOG), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9941

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y2C4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005107

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005098