Cyclophilin F (PPIF) (NM_005729) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

• Synonyms:

  Cyp-D; CyP-M; CYP3; CypD

• Gene ID:

  10105

• UniProt:

  P30405, A0A024QZS4

• Accession Number mRNA:

  NM_005729

• Chromosomal Location:

  10q22.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Molecular Weight:

  18.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PPIF

• Species:

  Human

• Protein ID:

  NP_005720

• Overview:

  Purified recombinant protein of Human peptidylprolyl isomerase F (PPIF), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10105

• Uniprot URL:

  https://www.uniprot.org/uniprot/P30405

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005729

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005720