NET1 (NM_005863) Human Recombinant Protein

• Background:

  This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

• Synonyms:

  ARHGEF8; NET1A

• Gene ID:

  10276

• UniProt:

  Q7Z628, Q5SQI7

• Accession Number mRNA:

  NM_005863

• Chromosomal Location:

  10p15.1

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Druggable Genome

• Molecular Weight:

  61.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NET1

• Species:

  Human

• Protein ID:

  NP_005854

• Overview:

  Purified recombinant protein of Human neuroepithelial cell transforming 1 (NET1), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10276

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q7Z628

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005863

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005854