NAPSIN A (NAPSA) (NM_004851) Human Recombinant Protein

• Background:

  This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]

• Synonyms:

  KAP; Kdap; NAP1; NAPA; SNAPA

• Gene ID:

  9476

• UniProt:

  O96009

• Accession Number mRNA:

  NM_004851

• Chromosomal Location:

  19q13.33

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Lysosome

• Field of Research:

  Lysosome

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, Protease

• Molecular Weight:

  42.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NAPSA

• Species:

  Human

• Protein ID:

  NP_004842

• Overview:

  Purified recombinant protein of Human napsin A aspartic peptidase (NAPSA), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9476

• Uniprot URL:

  https://www.uniprot.org/uniprot/O96009

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004851

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004842