LIN28B (NM_001004317) Human Recombinant Protein

• Background:

  The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

• Synonyms:

  CSDD2

• Gene ID:

  389421

• UniProt:

  Q6ZN17

• Accession Number mRNA:

  NM_001004317

• Chromosomal Location:

  6q16.3-q21

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  20mM PB, pH 7.4.

• Molecular Weight:

  26.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LIN28B

• Species:

  Human

• Protein ID:

  NP_001004317

• Overview:

  Purified recombinant protein of Human lin-28 homolog B (C. elegans) (LIN28B), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/389421

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6ZN17

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001004317

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001004317