PP2A-beta (PPP2CB) (NM_001009552) Human Recombinant Protein

• Background:

  This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]

• Synonyms:

  PP2Abeta; PP2CB

• Gene ID:

  5516

• UniProt:

  P62714, A0A140VJS0

• Accession Number mRNA:

  NM_001009552

• Chromosomal Location:

  8p12

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

• Field of Research:

  Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Druggable Genome, Phosphatase

• Molecular Weight:

  35.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PPP2CB

• Species:

  Human

• Protein ID:

  NP_001009552

• Overview:

  Purified recombinant protein of Human protein phosphatase 2, catalytic subunit, beta isozyme (PPP2CB), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5516

• Uniprot URL:

  https://www.uniprot.org/uniprot/P62714

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001009552

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001009552