ADA2a (TADA2A) (NM_001166105) Human Recombinant Protein

• Background:

  Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]

• Synonyms:

  ADA2; ADA2A; hADA2; KL04P; TADA2L

• Gene ID:

  6871

• UniProt:

  O75478, A0A024R0Y4

• Accession Number mRNA:

  NM_001166105

• Chromosomal Location:

  17q12

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Transcription Factors

• Molecular Weight:

  51.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TADA2A

• Species:

  Human

• Protein ID:

  NP_001159577

• Overview:

  Purified recombinant protein of Human transcriptional adaptor 2A (TADA2A), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6871

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75478

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001166105

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001159577