IMP3 (IGF2BP3) (NM_006547) Human Recombinant Protein

• Background:

  The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

• Synonyms:

  CT98; IMP-3; IMP3; KOC; KOC1; VICKZ3

• Gene ID:

  10643

• UniProt:

  O00425

• Accession Number mRNA:

  NM_006547

• Chromosomal Location:

  7p15.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Molecular Weight:

  63.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IGF2BP3

• Species:

  Human

• Protein ID:

  NP_006538

• Overview:

  Purified recombinant protein of Human insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10643

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00425

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006547

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006538