AGXT2 (NM_031900) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• Synonyms:

  AGT2; BAIBA; DAIBAT

• Gene ID:

  64902

• UniProt:

  Q9BYV1

• Accession Number mRNA:

  NM_031900

• Chromosomal Location:

  5p13.2

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Alanine, aspartate and glutamate metabolism

• Field of Research:

  Alanine, aspartate and glutamate metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome

• Molecular Weight:

  52.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AGXT2

• Species:

  Human

• Protein ID:

  NP_114106

• Overview:

  Purified recombinant protein of Human alanine--glyoxylate aminotransferase 2 (AGXT2), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/64902

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BYV1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_031900

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_114106