MTCH2 (NM_014342) Human Recombinant Protein

• Background:

  This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017]

• Synonyms:

  HSPC032; MIMP; SLC25A50

• Gene ID:

  23788

• UniProt:

  Q9Y6C9

• Accession Number mRNA:

  NM_014342

• Chromosomal Location:

  11p11.2

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

• Molecular Weight:

  59.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MTCH2

• Species:

  Human

• Protein ID:

  NP_055157

• Overview:

  Purified recombinant protein of Human mitochondrial carrier 2 (MTCH2), nuclear gene encoding mitochondrial protein, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23788

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6C9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014342

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055157