SNRPB (NM_003091) Human Recombinant Protein

• Background:

  The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB1

• Gene ID:

  6628

• UniProt:

  P14678, Q66K91

• Accession Number mRNA:

  NM_003091

• Chromosomal Location:

  20p13

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Related Pathways:

  Spliceosome, Systemic lupus erythematosus

• Field of Research:

  Spliceosome, Systemic lupus erythematosus

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

• Function:

  Stem cell - Pluripotency

• Molecular Weight:

  51.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SNRPB

• Species:

  Human

• Protein ID:

  NP_003082

• Overview:

  Purified recombinant protein of Human small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6628

• Uniprot URL:

  https://www.uniprot.org/uniprot/P14678

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003091

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003082