GNAT1 (NM_000172) Human Recombinant Protein

• Background:

  Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]

• Synonyms:

  CSNB1G; CSNBAD3; GBT1; GNATR

• Gene ID:

  2779

• UniProt:

  P11488, A1LQ23

• Accession Number mRNA:

  NM_000172

• Chromosomal Location:

  3p21.31

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea.

• Function:

  Druggable Genome

• Molecular Weight:

  39.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GNAT1

• Species:

  Human

• Protein ID:

  NP_000163

• Overview:

  Purified recombinant protein of Human guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 2, full length, with N-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2779

• Uniprot URL:

  https://www.uniprot.org/uniprot/P11488

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000172

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000163