DULLARD (CTDNEP1) (NM_015343) Human Recombinant Protein

• Background:

  Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  DULLARD; HSA011916; NET56

• Gene ID:

  23399

• UniProt:

  O95476

• Accession Number mRNA:

  NM_015343

• Chromosomal Location:

  17p13.1

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea.

• Function:

  Transmembrane

• Molecular Weight:

  56.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CTDNEP1

• Species:

  Human

• Protein ID:

  NP_056158

• Overview:

  Purified recombinant protein of Human CTD nuclear envelope phosphatase 1 (CTDNEP1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23399

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95476

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015343

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056158