C Fos (FOS) (NM_005252) Human Recombinant Protein

• Background:

  The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

• Synonyms:

  AP-1; C-FOS; p55

• Gene ID:

  2353

• UniProt:

  P01100, Q6FG41

• Accession Number mRNA:

  NM_005252

• Chromosomal Location:

  14q24.3

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Related Pathways:

  B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

• Field of Research:

  B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea.

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  68.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FOS

• Species:

  Human

• Protein ID:

  NP_005243

• Overview:

  Purified recombinant protein of uman FBJ murine osteosarcoma viral oncogene homolog (FOS), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2353

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01100

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005252

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005243