Cyclin C (CCNC) (NM_005190) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  CycC; hSRB11; SRB11

• Gene ID:

  892

• UniProt:

  P24863, Q7Z4L3

• Accession Number mRNA:

  NM_005190

• Chromosomal Location:

  6q16.2

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, pH8.0, 8M Urea.

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  61.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CCNC

• Species:

  Human

• Protein ID:

  NP_005181

• Overview:

  Purified recombinant protein of Human cyclin C (CCNC), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/892

• Uniprot URL:

  https://www.uniprot.org/uniprot/P24863

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005190

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005181