RSPO2 (NM_178565) Human Recombinant Protein

• Background:

  This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Synonyms:

  CRISTIN2; HHRRD; TETAMS2

• Gene ID:

  340419

• UniProt:

  Q6UXX9, B3KVP3

• Accession Number mRNA:

  NM_178565

• Chromosomal Location:

  8q23.1

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

• Function:

  Secreted Protein

• Molecular Weight:

  56.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RSPO2

• Species:

  Human

• Protein ID:

  NP_848660

• Overview:

  Purified recombinant protein of Human R-spondin 2 homolog (Xenopus laevis) (RSPO2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/340419

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6UXX9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_178565

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_848660