HS2ST1 (NM_012262) Human Recombinant Protein

• Background:

  Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]

• Synonyms:

  DJ604K5.2; NFSRA

• Gene ID:

  9653

• UniProt:

  Q7LGA3

• Accession Number mRNA:

  NM_012262

• Chromosomal Location:

  1p22.3

• Expression System:

  E. coli

• Tag:

  N-His-ABP

• Related Pathways:

  Heparan sulfate biosynthesis

• Field of Research:

  Heparan sulfate biosynthesis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

• Molecular Weight:

  24.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HS2ST1

• Species:

  Human

• Protein ID:

  NP_036394

• Overview:

  Purified recombinant protein of Human heparan sulfate 2-O-sulfotransferase 1 (HS2ST1), transcript variant 1, Asn29-His106, with N-terminal His-ABP tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9653

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q7LGA3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012262

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036394