Pyrin (MEFV) (NM_000243) Human Recombinant Protein

• Background:

  This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008]

• Synonyms:

  FMF; MEF; PAAND; TRIM20

• Gene ID:

  4210

• UniProt:

  O15553

• Accession Number mRNA:

  NM_000243

• Chromosomal Location:

  16p13.3

• Expression System:

  E. coli

• Tag:

  N-GST

• Related Pathways:

  NOD-like receptor signaling pathway

• Field of Research:

  NOD-like receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

• Function:

  Druggable Genome

• Molecular Weight:

  42.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MEFV

• Species:

  Human

• Protein ID:

  NP_000234

• Overview:

  Purified recombinant protein of Human Mediterranean fever (MEFV), transcript variant 1, Met1-Asn130, with N-terminal GST tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4210

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15553

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000243

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000234