LNX1 (NM_032622) Human Recombinant Protein

• Background:

  This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  LNX; MPDZ; PDZRN2

• Gene ID:

  84708

• UniProt:

  Q8TBB1

• Accession Number mRNA:

  NM_032622

• Chromosomal Location:

  4q12

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

• Function:

  Druggable Genome

• Molecular Weight:

  29.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LNX1

• Species:

  Human

• Protein ID:

  NP_116011

• Overview:

  Purified recombinant protein of Human ligand of numb-protein X 1 (LNX1), transcript variant 2, Met260-Val528, with N-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/84708

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8TBB1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032622

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_116011