TIMP3 (NM_000362) Human Recombinant Protein

• Background:

  This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM) . Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]

• Synonyms:

  HSMRK222; K222; K222TA2; SFD

• Gene ID:

  7078

• UniProt:

  P35625

• Accession Number mRNA:

  NM_000362

• Chromosomal Location:

  22q12.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  21.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TIMP3

• Species:

  Human

• Protein ID:

  NP_000353

• Overview:

  Purified recombinant protein of Human TIMP metallopeptidase inhibitor 3 (TIMP3), Cys24-End, with N-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7078

• Uniprot URL:

  https://www.uniprot.org/uniprot/P35625

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000362

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000353