HCG (CGA) (NM_000735) Human Recombinant Protein

• Background:

  The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

• Synonyms:

  CG-ALPHA; FSHA; GPA1; GPHa; GPHA1; HCG; LHA; TSHA

• Gene ID:

  1081

• UniProt:

  P01215, Q6I9S8

• Accession Number mRNA:

  NM_000735

• Chromosomal Location:

  6q14.3

• Expression System:

  E. coli

• Tag:

  N-His-Trx

• Related Pathways:

  Autoimmune thyroid disease, GnRH signaling pathway, Neuroactive ligand-receptor interaction

• Field of Research:

  Autoimmune thyroid disease, GnRH signaling pathway, Neuroactive ligand-receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

• Molecular Weight:

  30.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CGA

• Species:

  Human

• Protein ID:

  NP_000726

• Overview:

  Purified recombinant protein of Human glycoprotein hormones, alpha polypeptide (CGA), Ala25-End116, with N-terminal His-Trx tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1081

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01215

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000735

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000726