CHST11 (NM_018413) Human Recombinant Protein

• Background:

  The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t (12;14) (q23; q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

• Synonyms:

  C4ST; C4ST-1; C4ST1; HSA269537; OCBMD

• Gene ID:

  50515

• UniProt:

  Q9NPF2, A0A024RBL0

• Accession Number mRNA:

  NM_018413

• Chromosomal Location:

  12q23.3

• Expression System:

  E. coli

• Tag:

  N-His

• Related Pathways:

  Chondroitin sulfate biosynthesis, Sulfur metabolism

• Field of Research:

  Chondroitin sulfate biosynthesis, Sulfur metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Transmembrane

• Molecular Weight:

  34.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CHST11

• Species:

  Human

• Protein ID:

  NP_060883

• Overview:

  Purified recombinant protein of Human carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11), transcript variant 1, Val40-Leu330, with N-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/50515

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NPF2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_018413

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_060883