FIP200 (RB1CC1) (NM_014781) Human Recombinant Protein

• Background:

  The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

• Synonyms:

  ATG17; CC1; FIP200; PPP1R131

• Gene ID:

  9821

• UniProt:

  Q8TDY2

• Accession Number mRNA:

  NM_014781

• Chromosomal Location:

  8q11.23

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Druggable Genome

• Molecular Weight:

  40.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RB1CC1

• Species:

  Human

• Protein ID:

  NP_055596

• Overview:

  Purified recombinant protein of Human RB1-inducible coiled-coil 1 (RB1CC1), transcript variant 1, Ala1241-End, with N-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9821

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8TDY2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014781

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055596