EIF4A1 Rabbit pAb (APR30403N)

CAT: 0882-APR30403N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR30403N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality eIF4A1 Rabbit pAb (APR30403N) .

Synonyms

EIF4A1; DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I

Gene ID

1973

UniProt

P60842

Applications

IF (RD cell, Homo sapiens) IP (MESC) WB (Human cells, Mus musculus, Homo sapiens)

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:50 IP 1:20 - 1:50

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 39kDa/46kDa Observed MW: 45KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1973

Uniprot URL

https://www.uniprot.org/uniprot/P60842

AA Sequence

MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI

UniProtKB · P60842

Eukaryotic initiation factor 4A-I

IF4A1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P60842
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF4A1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-4A-I, eIF4A-I
EC number: 3.6.4.13
Processing: —
Secondary accessions: B2R6L8, D3DTP9, J3QLC4, P04765, Q5U018, Q61516

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembrane

Molecular function

HelicaseHydrolaseInitiation factorRNA-binding

Biological process

Host-virus interactionProtein biosynthesis

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