AMD1 Rabbit pAb (APR30141N)

CAT: 0882-APR30141N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR30141N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMD1 Rabbit pAb (APR30141N) .

Synonyms

AMD1; ADOMETDC; AMD; SAMDC

Gene ID

262

UniProt

P17707

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 21kDa/38kDa Observed MW: 32KDa/42KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=262

Uniprot URL

https://www.uniprot.org/uniprot/P17707

AA Sequence

RRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS

UniProtKB · P17707

S-adenosylmethionine decarboxylase proenzyme

DCAM_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P17707
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: AMD1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: AdoMetDC, SAMDC
EC number: 4.1.1.50
Processing: Precursor
Secondary accessions: E1P5F7, Q5VXN4, Q5VXN6, Q9BWK4

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Autocatalytic cleavagePhosphoproteinZymogen

Molecular function

DecarboxylaseLyase

Biological process

Polyamine biosynthesisSpermidine biosynthesis

Ligand

PyruvateS-adenosyl-L-methionineSchiff base

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A8537-01	AMD1 Rabbit pAb
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