[KO Validated] CD2BP2 Rabbit pAb (APR29464N)

CAT: 0882-APR29464N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR29464N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] CD2BP2 Rabbit pAb (APR24525N1) .

Synonyms

CD2BP2; FWP010; LIN1; PPP1R59; Snu40; U5-52K

Gene ID

10421

UniProt

O95400

Cellular Locus

Cytoplasm, Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 37kDa Observed MW: 50KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10421

Uniprot URL

https://www.uniprot.org/uniprot/O95400

AA Sequence

Email for sequence

UniProtKB · O95400

CD2 antigen cytoplasmic tail-binding protein 2

CD2B2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O95400
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CD2BP2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2
EC number: —
Processing: —
Secondary accessions: B2RDX2, Q9ULP2

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

CytoplasmNucleus

Biological process

mRNA processingmRNA splicing

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