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THBS2 Rabbit pAb (APR28340N)

CAT: 0882-APR28340N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR28340N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality THBS2 Rabbit pAb (APR28340N) .
Synonyms
THBS2; TSP2
Gene ID
7058
UniProt
P35442
Applications
IHC (Homo sapiens, Mus musculus) WB (Mus musculus)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 129kDa Observed MW: 150kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7058
Uniprot URL
https://www.uniprot.org/uniprot/P35442
AA Sequence
HQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFYEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQEL

UniProtKB · P35442

Thrombospondin-2

TSP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35442
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
THBS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A6H8N1, A7E232, Q5RI52
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

Calcium

Biological process

Cell adhesion

Disease

Disease variantEhlers-Danlos syndrome

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignal

Molecular function

Heparin-binding

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