DHDDS Rabbit pAb (APR27741N)

CAT: 0882-APR27741N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR27741N-01Size:50 µL

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Background

The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DHDDS Rabbit pAb (APR27741N) .

Synonyms

DHDDS; CIT; CPT; DS; HDS; RP59

Gene ID

79947

UniProt

Q86SQ9

Cellular Locus

Endoplasmic reticulum membrane, Peripheral membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 34kDa/38kDa Observed MW: 34kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=79947

Uniprot URL

https://www.uniprot.org/uniprot/Q86SQ9

AA Sequence

IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKCLYTNRSPHP

UniProtKB · Q86SQ9

Dehydrodolichyl diphosphate synthase complex subunit DHDDS

DHDDS_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q86SQ9
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: DHDDS
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.5.1.87
Processing: —
Secondary accessions: B7Z4B9, B7ZB20, D3DPK7, D3DPK8, D3DPK9, E9KL43, Q5T0A4, Q8NE90, Q9BTG5, Q9BTK3, Q9H905

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Congenital disorder of glycosylationDisease variantEpilepsyIntellectual disabilityRetinitis pigmentosa

Cellular component

Endoplasmic reticulumMembrane

Biological process

Lipid metabolism

Ligand

MagnesiumMetal-binding

Molecular function

Transferase

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