CSF3R Rabbit pAb (APR27586N)

CAT: 0882-APR27586N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR27586N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CSF3R Rabbit pAb (APR27586N) .

Synonyms

CSF3R; CD114; GCSFR; SCN7

Gene ID

1441

UniProt

Q99062

Cellular Locus

Cell membrane, Secreted, Single-pass type I membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 85kDa/86kDa/92kDa/95kDa Observed MW: 102kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1441

Uniprot URL

https://www.uniprot.org/uniprot/Q99062

AA Sequence

CSPNRKNPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQTYVLQGDPRAVSTQPQSQSGTSDQV

UniProtKB · Q99062

Granulocyte colony-stimulating factor receptor

CSF3R_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q99062
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CSF3R
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: G-CSF receptor, G-CSF-R
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneMembraneSecreted

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Receptor

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A7661-01	CSF3R Rabbit pAb
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