[KO Validated] CIB1 Rabbit pAb (APR25507N)

• Background:

  This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

• Synonyms:

  CIB1; CIB; CIBP; KIP1; PRKDCIP; SIP2-28

• Gene ID:

  10519

• UniProt:

  Q99828

• Cellular Locus:

  Apical cell membrane, Cell membrane, Cell projection, Cytoplasm, Golgi apparatus, Lipid-anchor, Membrane, Nucleus, centrosome, cytoskeleton, filopodium tip, growth cone, lamellipodium, microtubule organizing center, perinuclear region, ruffle membrane, sarcolemma, trans-Golgi network

• Applications:

  WB (Mus musculus) IHC (Mus musculus)

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 21kDa/26kDa Observed MW: 22kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] CIB1 Rabbit pAb (APR25507N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10519

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99828

• AA Sequence:

  MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFASSFKIVL