ECHS1 Rabbit pAb (APR25332N)

CAT: 0882-APR25332N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR25332N-01Size:50 µL

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Background

The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECHS1 Rabbit pAb (APR25332N) .

Synonyms

ECHS1; ECHS1D; SCEH

Gene ID

1892

UniProt

P30084

Cellular Locus

Mitochondrion matrix

Applications

WB (Homo sapiens)

Dilution

WB 1:1000 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 31kDa Observed MW: 31kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1892

Uniprot URL

https://www.uniprot.org/uniprot/P30084

AA Sequence

ASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ

UniProtKB · P30084

Enoyl-CoA hydratase, mitochondrial

ECHM_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P30084
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ECHS1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: mECH, mECH1
EC number: 4.2.1.17, 5.3.3.8
Processing: Precursor
Secondary accessions: O00739, Q5VWY1, Q96H54

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Disease

Disease variantNeurodegeneration

Biological process

Fatty acid metabolismLipid metabolism

Molecular function

IsomeraseLyase

Cellular component

Mitochondrion

Domain

Transit peptide

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