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CD23 Rabbit pAb (APR24390N)

CAT: 0882-APR24390N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR24390N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD23 Rabbit pAb (APR24390N) .
Synonyms
FCER2; BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
Gene ID
2208
UniProt
P06734
Cellular Locus
Cell membrane, Lipid-anchor, Secreted, Single-pass type II membrane protein
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 36kDa Observed MW: 36kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2208
Uniprot URL
https://www.uniprot.org/uniprot/P06734
AA Sequence
DTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS

UniProtKB · P06734

Low affinity immunoglobulin epsilon Fc receptor

FCER2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06734
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FCER2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumLectinMetal-binding

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinLipoproteinPalmitateProteoglycan

Molecular function

IgE-binding proteinReceptor

Domain

RepeatSignal-anchorTransmembraneTransmembrane helix