Cdc6 Rabbit pAb (APR24345N)

CAT: 0882-APR24345N-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0882-APR24345N-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cdc6 Rabbit pAb (APR24336N9) .

Synonyms

CDC18L; HsCDC6; MGORS5; HsCDC18; CDC6

Gene ID

990

UniProt

Q99741

Cellular Locus

Cytoplasm, Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 62kDa Observed MW: 62kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=990

Uniprot URL

https://www.uniprot.org/uniprot/Q99741

AA Sequence

Email for sequence

UniProtKB · Q99741

DNA replication factor CDC6

CDC6_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q99741
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CDC6
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q8TB30

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell divisionDNA replicationMitosis

Cellular component

CytoplasmNucleus

Disease

Disease variantDwarfism

PTM

PhosphoproteinUbl conjugation

Related Products

Catalog	Name
APR25345N-01	B4GALNT1 Rabbit pAb (APR25345N)
APR24445N-01	FMO3 Rabbit pAb (APR24445N)
APR24435N-01	LIPG Rabbit pAb (APR24435N)
APR24348N-01	ZCCHC7 Rabbit pAb (APR24348N)
APR24347N-01	NOP10 Rabbit pAb (APR24347N)
APR24343N-01	NOS2 Rabbit pAb (APR24343N)
APR24335N-01	MRPL38 Rabbit pAb (APR24335N)
APR24045N-01	VWC2 Rabbit pAb (APR24045N)
APR28345N-01	IER3 Rabbit pAb (APR28345N)
APR24395N-01	RPGR Rabbit pAb (APR24395N)

Alternative Products

Catalog	Name
MBS8542947-01	CDC6 Rabbit pAb
GTR18218419-01	Rabbit CDC6 Antibody
MBS4762466-01	CDC6 Rabbit mAb