SET1A Rabbit pAb (APR24327N)

CAT: 0882-APR24327N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR24327N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SET1A Rabbit pAb (APR24327N) .

Synonyms

Set1; KMT2F; Set1A; SETD1A; SET1A

Gene ID

9739

UniProt

O15047

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 186kDa Observed MW: 300kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9739

Uniprot URL

https://www.uniprot.org/uniprot/O15047

AA Sequence

Email for sequence

UniProtKB · O15047

Histone-lysine N-methyltransferase SETD1A

SET1A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O15047
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SETD1A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.1.1.364
Processing: —
Secondary accessions: A0A804HLA6, A6NP62, Q6PIF3, Q8TAJ6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorChromatin regulatorMethyltransferaseRNA-bindingTransferase

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantEpilepsyIntellectual disability

Biological process

DNA damageTranscriptionTranscription regulation

PTM

Phosphoprotein

Ligand

S-adenosyl-L-methionine

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