STEAP4 Rabbit pAb (APR23974N)

CAT: 0882-APR23974N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR23974N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+), using NAD (+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STEAP4 Rabbit pAb (APR23974N) .

Synonyms

STAMP2; SchLAH; TIARP; TNFAIP9; STEAP4

Gene ID

79689

UniProt

Q687X5

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 31kDa/51kDa Observed MW: 52kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=79689

Uniprot URL

https://www.uniprot.org/uniprot/Q687X5

AA Sequence

MEKTCIDALPLTMNSSEKQETVCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTTLLPSGAEVLSYSEAAKKSGIIIIAIHREHYDFLTELTEVLNGKI

UniProtKB · Q687X5

Metalloreductase STEAP4

STEA4_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q687X5
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: STEAP4
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 1.16.1.-
Processing: —
Secondary accessions: Q658Q9, Q687X4, Q8WWB0, Q9H5R1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeGolgi apparatusMembrane

Ligand

CopperFADFlavoproteinHemeIronMetal-bindingNADP

Biological process

Electron transportIon transportIron transportTransport

PTM

Glycoprotein

Molecular function

Oxidoreductase

Domain

TransmembraneTransmembrane helix

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