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MARK2 Rabbit pAb (APR23296N)

CAT: 0882-APR23296N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR23296N-01Size:50 µL
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Background
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MARK2 Rabbit pAb (APR23296N) .
Synonyms
MARK2; EMK-1; EMK1; PAR-1; Par-1b; Par1b
Gene ID
2011
UniProt
Q7KZI7
Cellular Locus
Cell membrane, Cytoplasm, Lateral cell membrane, Peripheral membrane protein, cytoskeleton
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 77-87kDa Observed MW: 78kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2011
Uniprot URL
https://www.uniprot.org/uniprot/Q7KZI7
AA Sequence
Email for sequence

UniProtKB · Q7KZI7

Serine/threonine-protein kinase MARK2

MARK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q7KZI7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MARK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1, 2.7.11.26
Processing
—
Secondary accessions
Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Ligand

ATP-bindingLipid-bindingMagnesiumMetal-bindingNucleotide-binding

Disease

Autism spectrum disorderDisease variantIntellectual disability

Cellular component

Cell membraneCell projectionCytoplasmCytoskeletonMembrane

Molecular function

Developmental proteinKinaseSerine/threonine-protein kinaseTransferase

Biological process

DifferentiationWnt signaling pathway

PTM

Phosphoprotein