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SPC24 Rabbit pAb (APR23204N)

CAT: 0882-APR23204N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR23204N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPC24 Rabbit pAb (APR23204N) .
Synonyms
SPC24; SPBC24
Gene ID
147841
UniProt
Q8NBT2
Cellular Locus
Chromosome, Nucleus, centromere, kinetochore
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 17kDa/22kDa Observed MW: 22kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=147841
Uniprot URL
https://www.uniprot.org/uniprot/Q8NBT2
AA Sequence
MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDTEW

UniProtKB · Q8NBT2

Kinetochore protein Spc24

SPC24_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NBT2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPC24
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hSpc24
EC number
—
Processing
—
Secondary accessions
B4DZZ7, C9JGC4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosis

Cellular component

CentromereChromosomeKinetochoreNucleus

Domain

Coiled coil

PTM

Phosphoprotein