EBF3 Rabbit pAb (APR22564N)

CAT: 0882-APR22564N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR22564N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EBF3 Rabbit pAb (APR22564N) .

Synonyms

EBF3; COE3; EBF-3; HADDS; O/E-2; OE-2

Gene ID

253738

UniProt

Q9H4W6

Cellular Locus

Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 60kDa/64kDa Observed MW: 58kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=253738

Uniprot URL

https://www.uniprot.org/uniprot/Q9H4W6

AA Sequence

AEALYSVPRNHNQIPTLGNNPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTPQQSNYNTVSTSMNGYGSGAMASLGVPGSPGF

UniProtKB · Q9H4W6

Transcription factor COE3

COE3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9H4W6
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EBF3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A0AUY1, Q5T6H9, Q9H4W5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Disease variantIntellectual disability

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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E45R22564N	EBF3 Rabbit pAb
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