MVB12A Rabbit pAb (APR22520N)

CAT: 0882-APR22520N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR22520N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MVB12A Rabbit pAb (APR22520N) .

Synonyms

MVB12A; CFBP; FAM125A

Gene ID

93343

UniProt

Q96EY5

Cellular Locus

Cytoplasm, Endosome, Late endosome membrane, Nucleus, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 24kDa/27kDa/28kDa Observed MW: 29kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=93343

Uniprot URL

https://www.uniprot.org/uniprot/Q96EY5

AA Sequence

MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLGSLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFGDLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS

UniProtKB · Q96EY5

Multivesicular body subunit 12A

MB12A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q96EY5
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MVB12A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q96I18

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeletonEndosomeMembraneNucleus

PTM

Phosphoprotein

Biological process

Protein transportTransport

Domain

SH3-binding

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