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DYNC1I2 Rabbit pAb (APR21275N)

CAT: 0882-APR21275N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR21275N-01Size:50 µL
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Background
This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DYNC1I2 Rabbit pAb (APR21275N) .
Synonyms
DYNC1I2; DIC74; DNCI2; IC2
Gene ID
1781
UniProt
Q13409
Cellular Locus
Cytoplasm, cytoskeleton
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 68kDa/70kDa/71kDa Observed MW: 71-105kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1781
Uniprot URL
https://www.uniprot.org/uniprot/Q13409
AA Sequence
AAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA

UniProtKB · Q13409

Cytoplasmic dynein 1 intermediate chain 2

DC1I2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13409
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DYNC1I2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7ZA04, D3DPD4, D3DPD5, D3DPD6, Q32LY9, Q53S84, Q5BJF8, Q7Z4X1, Q96NG7, Q96S87, Q9BXZ5, Q9NT58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeletonDyneinMicrotubule

Disease

Disease variantIntellectual disability

Biological process

Host-virus interactionTransport

Molecular function

Motor protein

Domain

RepeatWD repeat

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