PHC2 Rabbit pAb (APR21169N)

CAT: 0882-APR21169N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR21169N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PHC2 Rabbit pAb (APR21169N) .

Synonyms

PHC2; EDR2; HPH2; PH2

Gene ID

1912

UniProt

Q8IXK0

Cellular Locus

Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 30kDa/35kDa/87kDa/90kDa Observed MW: 45kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1912

Uniprot URL

https://www.uniprot.org/uniprot/Q8IXK0

AA Sequence

HFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS

UniProtKB · Q8IXK0

Polyhomeotic-like protein 2

PHC2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q8IXK0
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PHC2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: hPH2
EC number: —
Processing: —
Secondary accessions: A1L4Q1, A8KA40, D3DPR2, Q2TAL3, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7

Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Developmental proteinDNA-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

Zinc-finger

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